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June 12, 2026Journal of Endocrinology and MetabolismOpen Access

The Role of Intermittent Fasting in Modulating Hormonal Biomarkers in Women With Polycystic Ovary Syndrome: A Review

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Authors

IUIdayakshini UlaganathanIKIyshwarya Bhaskar KalaraniMMMadhumitha Masilamani

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Overview

Review evaluates intermittent fasting effects on hormonal and metabolic biomarkers in women with PCOS, suggesting potential benefits.

Key Points

  • This review evaluates the impact of intermittent fasting on hormonal and metabolic biomarkers in women with polycystic ovary syndrome (PCOS).
  • Evaluated effects of intermittent fasting interventions: time-restricted feeding, alternate-day fasting, and the 5:2 fasting model.
  • Focused on hormonal, metabolic, and inflammatory biomarkers in women with PCOS.
  • Included human studies and mechanistic research for analysis.
  • Intermittent fasting significantly improves insulin sensitivity and reduces hyperandrogenism.
  • Supports weight loss and enhances menstrual regularity and ovulation.
  • Inconsistently reported hormonal changes in estrogen, LH, and FSH levels, with mechanisms involving AMPK activation and mTOR suppression.

Cite This Study

Ulaganathan et al. (2026) studied this question.

synapsesocial.com/papers/6a2ba2c18101cf8926f019d5https://doi.org/10.14740/jem1568
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effect of Intermittent Fasting on Anthropometric Measurements, Metabolic Profile, and Hormones in Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis2025 · 9 citations
  2. 2The Impact of Intermittent Fasting on Metabolic and Hormonal Profile in Patients with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis2025
  3. 3Intermittent Fasting and Hormonal Regulation: Pathways to Improved Metabolic Health2025
  4. 4The Impact of Low-Calorie Dietary Patterns on Polycystic Ovary Syndrome with Insulin Resistance2025
  5. 5Effects of Intermittent Fasting on Male and Female Reproductive Hormones, Fertility, and Sexual Function: A Comprehensive Review with Emphasis on the Existing Evidence Gap in Women2026 · 2 citations