What question did this study set out to answer?

This research aims to develop and validate eco-friendly chromatographic methods for estimating active ingredients in a cold and flu formulation.

June 12, 2026Scientific ReportsOpen Access

Green and applicable chromatographic approaches for the estimation of a multi-component cold and flu relief formulation along with in-vitro dissolution profiling

View Full Paper

Ask AI

Bookmark

Authors

MNMona NabilCairo University HMHoda M. MarzoukCairo University SASamah S. AbbasCairo University

Discussion

Member takes

Implication

Randomized trial demonstrates reliable quantification of active ingredients in a multi-component relief formulation, suggesting ecological sustainability benefits.

Key Points

This research aims to develop and validate eco-friendly chromatographic methods for estimating active ingredients in a cold and flu formulation.
Established two chromatographic methodologies: HPTLC and HPLC.
Employed specific solvents and conditions for both methods ensuring high precision and accuracy.
Validated methods according to International Conference on Harmonization guidelines.
HPTLC achieved resolutions of 8.44 and 4.57 for PHE and IBU/CPM, respectively.
HPLC demonstrated resolutions of 7.62 and 3.21 for PHE and IBU/CPM within a 6-minute run time.
Limit of detection values were 0.02 µg/band for PHE and 0.03 µg/mL for PHE in HPTLC and HPLC, respectively.

Cite This Study

Nabil et al. (2026) studied this question.

synapsesocial.com/papers/6a2ba2f68101cf8926f01b9a https://doi.org/10.1038/s41598-026-55497-7

View Full Paper

Ask AI

Bookmark

Implication

Randomized trial demonstrates reliable quantification of active ingredients in a multi-component relief formulation, suggesting ecological sustainability benefits.

Green and applicable chromatographic approaches for the estimation of a multi-component cold and flu relief formulation along with in-vitro dissolution profiling

Discussion

Member takes

Implication

Key Points

Cite This Study

Green and applicable chromatographic approaches for the estimation of a multi-component cold and flu relief formulation along with in-vitro dissolution profiling

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider