Retrospective cohort study shows early enteral nutrition reduces hospital stay in adults with severe acute pancreatitis, suggesting therapeutic benefits.
BACKGROUND: To investigate the impact of early enteral nutrition on hospital stay in adults with severe acute pancreatitis (SAP). METHODS: Retrospective analysis of clinical data from adult SAP patients admitted between January 2023 and June 2023. Patients were divided into early enteral nutrition (63 cases) and late enteral nutrition (69 cases) groups. General information, admission blood parameters, white blood cell count, CRP levels, and length of hospital stay were compared between the groups. Pearson correlation analysis explored the relationship between timing of enteral nutrition and hospital stay. RESULTS: No significant differences in general information and admission blood parameters between groups. Both groups showed significant decreases in white blood cell count (WBC) and CRP levels following the initiation of enteral nutrition. After enteral nutrition intervention, the early enteral nutrition group had significantly lower WBC and CRP concentration than the late enteral nutrition group. Average length of hospital stay and ICU stay were significantly shorter in the early enteral nutrition group. Correlation analysis showed a positive correlation between timing of enteral nutrition and average length of hospital stay and ICU stay in SAP patients. CONCLUSIONS: Early enteral nutrition has significant advantages over late enteral nutrition in improving inflammatory response and reducing length of hospital stay and ICU stay.
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Li et al. (2026) studied this question.
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