Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
June 12, 2026ACS OmegaOpen Access

Recent Advances in Dopamine Receptor Ligands as Chemical Biology Tools

View Full Paper
Ask AI
Bookmark
Share

Authors

MDMichael DoroganUniversity of PittsburghNKNamballa Hari KrishnaCity University of New YorkSPSandip PatraThe Graduate Center, CUNY

Discussion

Loading...

Member takes

Implication

Review highlights developments in dopamine receptor ligands, suggesting implications for drug discovery.

Key Points

  • This review explores the advancements in dopamine receptor ligands and their potential as chemical biology tools.
  • Review of recent literature on dopamine receptor ligands.
  • Examination of various types of ligands including bivalent, photoactivatable, and photoswitchable ligands.
  • Discussion of the challenges in developing selective ligands for dopamine receptors.
  • Recent advancements in selective dopamine receptor ligands could improve drug development.
  • New classes of ligands such as fluorescent probes enhance drug targeting and monitoring.
  • Innovative tools may lead to better understanding of dopamine-related disorders.

Cite This Study

Dorogan et al. (2026) studied this question.

synapsesocial.com/papers/6a2ba34a8101cf8926f0208ehttps://doi.org/10.1021/acsomega.6c01474
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Physiology and Pharmacology of Striatal Neurons2009 · 548 citations
  2. 2Ultrafast neuronal imaging of dopamine dynamics with designed genetically encoded sensors2018 · 1,195 citations
  3. 3Allosteric Modulators: An Emerging Concept in Drug Discovery2015 · 95 citations
  4. 4The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints2003 · 2,979 citations
  5. 5Structure-guided development of heterodimer-selective GPCR ligands2016 · 99 citations