Case report reveals a rare tumour causing phosphate wastage in a subcutaneous inguinal lesion, suggesting effective detection methods.
Tumour-induced osteomalacia (TIO) is a rare paraneoplastic syndrome caused by excess fibroblast growth factor-23 (FGF23), leading to renal phosphate wasting and hypophosphatemia. Patients present with nonspecific bone pain, muscle weakness, and fractures, resulting in significant diagnostic delays. Benign phosphaturic mesenchymal tumours are causative and are commonly located in the bones and soft tissues of the lower limbs and the head and neck. Complete surgical excision is curative, emphasising the need for lesion localisation. We present a rare case of a subcutaneously located lesion in the uncommonly reported inguinal region. Functional imaging utilising 68 Ga-DOTANOC PET/CT offers unparalleled detection rates in this pathology.
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Kaur et al. (2026) studied this question.
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