What question did this study set out to answer?

Assess the prognostic value of inflammatory and nutritional indices in older gastric cancer patients undergoing radical gastrectomy.

June 12, 2026Clinical Interventions in AgingOpen Access

Preoperative PNI-dNLR Score as Predicting Long-Term Survival in Older Adults Undergoing Radical Gastrectomy for Gastric Cancer

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Authors

XCXun-Lin ChenFujian Medical University XZXi ZhangGeneral Cardiology ZLZhixin LinSouth China Agricultural University

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Implication

Retrospective analysis identifies the PNI-dNLR score as a strong predictor of survival in elderly gastric cancer patients, suggesting it could aid in treatment planning.

Key Points

Assess the prognostic value of inflammatory and nutritional indices in older gastric cancer patients undergoing radical gastrectomy.
Retrospective single-center analysis of 609 older adults diagnosed with gastric cancer (2012-2020)
Constructed the PNI-dNLR score using preoperative PNI and dNLR
Used multivariate Cox regression to identify independent prognostic factors
Preoperative PNI showed HR of 0.74 (95% CI, 0.57-0.97; p=0.027) for overall survival
dNLR exhibited HR of 1.44 (95% CI, 1.06-1.94; p=0.018) as a prognostic indicator
The PNI-dNLR score had favorable predictive performance and remained significant in multivariate analyses (p<0.05)

Cite This Study

Chen et al. (2026) studied this question.

synapsesocial.com/papers/6a2ba3d18101cf8926f026cd https://doi.org/10.2147/cia.s607241

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Implication

Retrospective analysis identifies the PNI-dNLR score as a strong predictor of survival in elderly gastric cancer patients, suggesting it could aid in treatment planning.

Preoperative PNI-dNLR Score as Predicting Long-Term Survival in Older Adults Undergoing Radical Gastrectomy for Gastric Cancer

Discussion

Member takes

Implication

Key Points

Cite This Study

Preoperative PNI-dNLR Score as Predicting Long-Term Survival in Older Adults Undergoing Radical Gastrectomy for Gastric Cancer

Discussion

Member takes

Implication

Key Points

Cite This Study

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