Key result
Passive leg raising alters FTc, IVC diameter, BP, and HR regardless of fasting status.
Why the study?
Assessing the necessity for fluid resuscitation is critical in the emergency department, and sonography offers a less-invasive, reproducible diagnostic modality.
Does passive leg raising alter corrected carotid flow time and inferior vena cava diameter in healthy individuals?
Cross-Sectional (n=72)
Does passive leg raising alter corrected carotid flow time and inferior vena cava diameter in healthy individuals?
p-value: p=<0.001
Corrected carotid flow time (FTc) measured via ultrasound changes significantly with passive leg raising and correlates with IVC collapsibility, supporting its use as a marker for intravascular volume status.
Background and Aim Assessing the necessity for fluid resuscitation is critical in the emergency department, and sonography provides a less‐invasive, reproducible diagnostic modality for this purpose. This study aims to evaluate intravascular volume status in healthy individuals by analyzing alterations in corrected carotid flow time (FTc) and inferior vena cava (IVC) diameter via ultrasound before and after passive leg raising (PLR). Methods This prospective observational study was conducted with healthy individuals who underwent a 12‐h fasting protocol. Participants voluntarily fasted, and we measured variations in blood pressure, heart rate, FTc, and IVC diameter before and after PLR in both fasting and non‐fasting conditions. Results A total of 72 healthy male subjects were enrolled in the study. Statistically significant differences were observed in all measured parameters—blood pressure, heart rate, FTc, and IVC diameter—before and after PLR in both fasting and non‐fasting states ( p < 0.001). Furthermore, a significant inversely correlation was identified between the increase in FTc and the reduction in IVC collapsibility following PLR (fasting: p = −0.567, p < 0.001; non‐fasting: p = −0.301, p = 0.010). Conclusion FTc can be utilized as a reliable marker for assessing intravascular volume status, demonstrating a positive correlation with intravenous fluid administration. This index, when combined with other criteria for evaluating hemodynamic status, is effective for assessing patients' volume status.
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Golikhatir et al. (2026) conducted a cross-sectional in Healthy individuals (n=72). Passive leg raising vs. Before passive leg raising was evaluated on Alterations in blood pressure, heart rate, corrected carotid flow time (FTc), and inferior vena cava (IVC) diameter (p=<0.001). Passive leg raising significantly altered corrected carotid flow time, inferior vena cava diameter, blood pressure, and heart rate in both fasting and non-fasting states (p<0.001).
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