What question did this study set out to answer?

To assess the utility of the basophil activation test in confirming cephalosporin allergy in a patient with allergic reactions to cefotaxime and cefixime.

June 12, 2026Laboratory Medicine

Basophil activation test in the assessment of cephalosporin allergy: a case report

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Authors

RMRania MzoughiUniversity of Carthage BHBaraa Ben HouriaMilitary Hospital of Tunis MHMahmoud HchafMilitary Hospital of Tunis

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Implication

Case report reveals basophil activation test confirms hypersensitivity to cephalosporins, suggesting reliable diagnosis methods.

Key Points

To assess the utility of the basophil activation test in confirming cephalosporin allergy in a patient with allergic reactions to cefotaxime and cefixime.
Case report of a 33-year-old woman with an allergic reaction to cefotaxime and cefixime.
Use of basophil activation test to confirm immunoglobulin E-mediated hypersensitivity.
Clinical observation of allergic symptoms and their resolution after drug discontinuation.
Patient developed skin rash and pruritus after cefotaxime and cefixime administration.
Basophil activation test was positive, confirming type I hypersensitivity reaction to cephalosporins.
Symptoms resolved after discontinuation of the drugs.

Cite This Study

Mzoughi et al. (2026) studied this question.

synapsesocial.com/papers/6a2ba4778101cf8926f02e6c https://doi.org/10.1093/labmed/lmag033

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Basophil activation test in the assessment of cephalosporin allergy: a case report

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Key Points

Cite This Study

Basophil activation test in the assessment of cephalosporin allergy: a case report

Discussion

Member takes

Implication

Key Points

Cite This Study

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