What question did this study set out to answer?

The study aimed to evaluate tissue damage during balloon angioplasty and stenting in neonatal coarctation of the aorta.

June 12, 2026Scientific ReportsOpen Access

Quantitative assessment of microstructural damage in paediatric aortic coarctation tissue during benchtop balloon angioplasty and stenting

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The study aimed to evaluate tissue damage during balloon angioplasty and stenting in neonatal coarctation of the aorta.
Conducted an ex vivo study using neonatal coarctation samples obtained from surgery.
Performed balloon angioplasty and stenting, visualizing deformation using ultrasound guidance.
Assessed collagen damage using collagen hybridizing peptide (CHP).
Balloon angioplasty was not viable for maintaining vessel patency without achieving very high stretch levels.
Five out of six samples were successfully stented without stent failures, indicating stenting is effective for lumen gain.
Both procedures caused significant collagen damage to the tissue.

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Implication

Ex vivo study investigates tissue damage from balloon angioplasty and stenting in neonatal coarctation of the aorta, suggesting careful stent expansion to minimize harm.

Cite This Study

Linnane et al. (2026) studied this question.

synapsesocial.com/papers/6a2ba4a18101cf8926f03011 https://doi.org/10.1038/s41598-026-57357-w

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Implication

Ex vivo study investigates tissue damage from balloon angioplasty and stenting in neonatal coarctation of the aorta, suggesting careful stent expansion to minimize harm.

Quantitative assessment of microstructural damage in paediatric aortic coarctation tissue during benchtop balloon angioplasty and stenting

Key Points

Discussion

Implication

Cite This Study

Quantitative assessment of microstructural damage in paediatric aortic coarctation tissue during benchtop balloon angioplasty and stenting

Key Points

Discussion

Implication

Cite This Study

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