Key result
Breast radiotherapy with deep inspiration breath-hold limits maximum pacemaker dose below 2.0 Gy without malfunction.
Why the study?
Radiation therapy planning is complex in pacemaker-dependent breast cancer patients, as device radiation exposure can lead to malfunction with serious clinical consequences.
Can adjuvant breast radiotherapy be delivered safely without device malfunction in pacemaker-dependent patients using 6 MV photon beams and DIBH techniques?
Design
Retrospective review
Authors
Loading...
Supports feasibility of safe adjuvant RT in pacemaker-dependent patients; leaves open need for larger prospective validation.
Observational (n=5)
No
Can adjuvant breast radiotherapy be delivered safely without device malfunction in pacemaker-dependent patients using 6 MV photon beams and DIBH techniques?
Adjuvant breast radiotherapy can be safely delivered to pacemaker-dependent patients using low-energy photon beams, DIBH, and meticulous dosimetric planning without compromising device functionality.
Singh et al. (2026) conducted an observational in Breast cancer in pacemaker-dependent patients (n=5). Adjuvant external beam radiation therapy with DIBH was evaluated on Target coverage (PTV V95%). Adjuvant breast radiotherapy using deep inspiration breath-hold in pacemaker-dependent patients achieved excellent target coverage (PTV V95% = 96.8%) while keeping the maximum pacemaker dose below 2.0 Gy without device malfunction.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: