Overview of treatment options for narcolepsy, highlighting effectiveness of drugs and behavioral strategies.
This paper presents an overview of current pharmacological and non-pharmacological treatment options available for narcolepsy. Antidepressant medications, including selective serotonin reuptake inhibitors and selective serotonin and norepinephrine reuptake inhibitors, have demonstrated efficacy in mitigating cataplexy episodes. Additionally, various pharmaceutical agents, including psychostimulants and anesthetics, are effective in alleviating excessive daytime sleepiness. Among the behavioral interventions for narcolepsy, adherence to a consistent sleep schedule and the incorporation of scheduled naps throughout the day remain the most widely implemented strategies.
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Gorbachev et al. (2026) studied this question.
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