Cerebral Embolic Protection Devices in Transcatheter Aortic Valve Implantation: A Systematic Review and Meta-analysis of Randomized Controlled Trials (P5-4.020)

Rowaid Ahmad; Hassan Waseem; Zain ul Abideen; Muhammad Osama; Muhammad Haseeb Khan; Rabeya Farid; Nohela Rehman; Muhammad Ansari; Muhammad Ansari; Justin Chih-Yao Chen; Jamir Pitton Rissardo; Ana Letícia Fornari Caprara; Vishnu Byroju; Adam Dmytriw; Brandon Lucke‐Wold

doi:10.1212/wnl.0000000000212995

June 9, 2026Neurology

Cerebral Embolic Protection Devices in Transcatheter Aortic Valve Implantation: A Systematic Review and Meta-analysis of Randomized Controlled Trials (P5-4.020)

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Key result

Cerebral embolic protection devices show inconclusive safety and efficacy outcomes during TAVI.

Key Points

To assess the overall efficacy and safety profile of cerebral embolic protection devices in patients receiving transcatheter aortic valve implantation.
Conducted a systematic review and meta-analysis synthesizing data exclusively from randomized controlled trials.
Evaluated neuroprotective endpoints and adverse procedural outcomes comparing valve implantation with versus without cerebral embolic protection devices.
Analyzed pooled neurological outcomes, focusing on the prevention of cerebral ischemic events and stroke risk reduction following valve deployment (specific numerical effect sizes not reported in abstract).
Characterized the relative procedural safety and device-related complication rates across randomized clinical cohorts.

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Implication

Meta-analysis evaluates the clinical efficacy and safety of cerebral embolic protection devices in patients undergoing aortic valve replacement, highlighting stroke prevention strategies.

Abstract

This meta-analysis evaluated the effectiveness and safety of cerebral embolic protection devices (CEPDs) in patients undergoing transcatheter aortic valve implantation (TAVI).

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Cite This Study

Ahmad et al. (2026) studied this question. Cerebral embolic protection devices were evaluated for effectiveness and safety in patients undergoing transcatheter aortic valve implantation, but the abstract lacks specific results.

synapsesocial.com/papers/6a2bb3b68101cf8926f038c9 https://doi.org/10.1212/wnl.0000000000212995

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Cerebral Embolic Protection Devices in Transcatheter Aortic Valve Implantation: A Systematic Review and Meta-analysis of Randomized Controlled Trials (P5-4.020)

Key Points

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Implication

Abstract

Discussion

Cite This Study

Cerebral Embolic Protection Devices in Transcatheter Aortic Valve Implantation: A Systematic Review and Meta-analysis of Randomized Controlled Trials (P5-4.020)

Key Points

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Implication

Abstract

Discussion

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