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June 12, 2026Clinical and Applied Thrombosis/HemostasisOpen Access

Knowledge Drives Venous Thromboembolism Prevention: Structural Equation Modeling Insights Into Physicians’ Knowledge, Attitudes and Practices in Chinese Public Hospitals

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Key result

Greater physician knowledge is strongly linked to VTE prevention practices, with attitude facilitating translation.

  • β = 0.50
  • P<0.05
  • n=787

Why the study?

Venous thromboembolism is a preventable cause of cardiovascular mortality in hospitalized patients, but prophylaxis remains underutilized.

Population

787 physicians in Chinese public hospitals

Design

Cross-sectional multicenter online survey

Authors

WDWei DiYWYuan WuYWYì Wáng

Discussion

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Overview

Knowledge was associated with VTE prevention practices; leaves open whether education improves adherence in Chinese hospitals.

Key Points

  • This study investigates physicians’ knowledge, attitudes, and practices regarding VTE prevention in Chinese public hospitals.
  • Cross-sectional, multicenter online survey of physicians in Chinese public hospitals.
  • KAP-based questionnaire assessed physician knowledge, attitudes, and practices.
  • Data analyzed using descriptive statistics, Pearson correlations, and structural equation modeling.
  • KAP scores were positive but knowledge of key tools like intermittent pneumatic compression was low (3.40 ± 1.24).
  • Knowledge directly influenced practice (β = 0.50, P < 0.05) and attitudes facilitated knowledge-to-practice translation (β = 0.25, P < 0.05).
  • Positive correlations among KAP domains (r = 0.35 – 0.59, P < 0.001).

Study Design

Type

Cross-Sectional (n=787)

Multicenter

Yes

Structured PICO

P
Population
787 physicians in Chinese public hospitals surveyed on their knowledge, attitudes, and practices regarding venous thromboembolism prevention.
O
Outcome
Physicians' knowledge, attitudes, and practices (KAP) regarding VTE prevention and their interrelationships

Main Result

Effect estimate: β = 0.50

p-value: p=<0.05

Physicians' knowledge directly influences VTE prophylaxis practices, with attitudes facilitating this translation, highlighting the need for targeted training on risk assessment tools.

Limitations

  • Predominance of tertiary public hospital respondents limits generalizability
  • Predominance of tertiary public hospital respondents, limiting generalizability

Cite This Study

Di et al. (2026) conducted a cross-sectional in Venous thromboembolism prevention (n=787). Knowledge of VTE prevention was evaluated on Influence of knowledge on practice (β = 0.50, p=<0.05). Physicians' knowledge directly influenced VTE prevention practices (β = 0.50, P < 0.05), with attitude facilitating knowledge-to-practice translation.

synapsesocial.com/papers/6a2bd11d6550ea4541ffe877https://doi.org/10.1177/10760296261460578
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Knowledge, attitudes, and practices of patients with lower limb fractures post-surgery regarding deep vein thrombosis2025 · 4 citations
  2. 2VTE Risk Profiles and Prophylaxis in Medical and Surgical Inpatients2018 · 107 citations
  3. 3Effect of Real-time Patient-Centered Education Bundle on Administration of Venous Thromboembolism Prevention in Hospitalized Patients2018 · 53 citations
  4. 4European guidelines on peri-operative venous thromboembolism prophylaxis: first update.2024 · 7 citations
  5. 5The Clots in Legs Or sTockings after Stroke (CLOTS) 3 trial: a randomised controlled trial to determine whether or not intermittent pneumatic compression reduces the risk of post-stroke deep vein thrombosis and to estimate its cost-effectiveness2015 · 104 citations