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June 12, 2026European Journal of Preventive CardiologyOpen Access

How to reach all patients after discharge for acute coronary syndrome? nursing as a key component

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Key result

Nurse-led telephone follow-up achieves early LDL-C targets in 54% of ACS patients.

  • n=88

Why the study?

Does a secondary prevention program with telephone follow-up conducted by nursing staff improve cardiovascular risk factor targets in patients discharged after ACS who are not enrolled in cardiac rehabilitation programs?

Population

88 patients discharged after ACS not enrolled in cardiac rehabilitation programs

Comparison

Secondary prevention program with telephone follow-up conducted by nursing staff

Design

Prospective descriptive single-center observational study

Follow-up

1 year

Authors

RVR S V Rocio Sanchez VacaBBB C V Calvo BernalMTM M T Miriam Martin Toro

Discussion

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Overview

Suboptimal LDL-C control persists despite therapy; challenges guideline implementation and extends need for targeted optimization strategies.

Key Points

  • To assess the impact of a secondary prevention program with nursing telephone follow-up on patients discharged after acute coronary syndrome who did not enroll in cardiac rehabilitation programs.
  • Prospective single-center observational study
  • Follow-up at 4–6 weeks and 1 year post-discharge
  • Assessment of LDL-C, non-HDL-C, and HbA1c targets, and eligibility for dual antiplatelet therapy.
  • 54% achieved LDL-C targets at 4–6 weeks, stable at 1 year (61.2 ± 30 mg/dL at 4–6 weeks, 61 ± 32 mg/dL at 1 year)
  • Non-HDL-C control improved from 58% at 4–6 weeks to 70% at 1 year (85 ± 36 mg/dL at 4–6 weeks, 79 ± 41 mg/dL at 1 year)
  • 62% achieved HbA1c control at 4–6 weeks, rising to 68% at 1 year (6.9 ± 1.5% at 4–6 weeks, 6.6 ± 1.1% at 1 year).

Study Design

Type

Observational (n=88)

Multicenter

No

Structured PICO

Does a secondary prevention program with telephone follow-up conducted by nursing staff improve cardiovascular risk factor targets in patients discharged after ACS who are not enrolled in cardiac rehabilitation programs?

P
Population
88 patients (mean age 78, 38% women) discharged after acute coronary syndrome who were not enrolled in cardiac rehabilitation programs, followed for 1 year.
E
Exposure
Secondary prevention program with telephone follow-up conducted by nursing staff.
O
Outcome
Achievement of LDL-C, non-HDL-C, and glycated hemoglobin (HbA1c) targets at 4-6 weeks and 1 year.surrogate

A nursing-led telephone follow-up program for secondary prevention in post-ACS patients not enrolled in cardiac rehabilitation achieved favorable cardiovascular risk factor control.

Limitations

  • Elderly population with multiple comorbidities, high rate of recurrent events, and substantial polypharmacy

Cite This Study

Vaca et al. (2026) conducted an observational in Acute coronary syndrome (n=88). Secondary prevention program with telephone follow-up by nursing staff was evaluated on Achievement of LDL-C targets at 4-6 weeks. A secondary prevention program with nursing telephone follow-up for ACS patients achieved LDL-C targets in 54% at 4-6 weeks, with an 18.1% event rate over 1 year.

synapsesocial.com/papers/6a2bd11d6550ea4541ffe883https://doi.org/10.1093/eurjpc/zwag249.018
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Benefits of a Comprehensive Cardiac Rehabilitation Program for Patients with Acute Coronary Syndrome: A Follow-Up Study2023 · 8 citations
  2. 2Secondary prevention therapies in acute coronary syndrome and relation to outcomes: observational study2019 · 40 citations
  3. 3ACS Program. Improving secondary prevention in patients admitted due to a myocardial infarction. First year experience2024 · 1 citations
  4. 4Cardiovascular risk factor control in acute coronary syndrome survivors in a cardiac rehabilitation program - are we achieving sustained results?2024
  5. 5Optimizing cardiovascular risk control after an acute coronary syndrome: the role of a structured follow-up program2025