Key result
CKD linked to higher postoperative complications, CV events, and mortality in abdominal surgery.
Why the study?
Individuals with chronic kidney disease undergoing abdominal surgery face higher risks of postoperative complications, including cardiovascular events, acute kidney injury, and hospital mortality.
What is the clinical significance of chronic kidney disease as a risk factor for adverse postoperative outcomes in abdominal surgery?
What is the clinical significance of chronic kidney disease as a risk factor for adverse postoperative outcomes in abdominal surgery?
This review emphasizes the elevated perioperative risk in CKD patients undergoing abdominal surgery and highlights the need for tailored perioperative assessment and management to reduce complications.
CKD patients face higher abdominal surgery complication risks; supports risk stratification but leaves optimal strategies open for prospective trials.
Chronic kidney disease (CKD) represents a major global health burden and is associated with increased morbidity, mortality, and adverse outcomes in surgical patients. Individuals with CKD undergoing abdominal surgery demonstrate a significantly higher risk of postoperative complications, including acute kidney injury, infectious complications, cardiovascular events, and increased hospital mortality. Reduced renal functional reserve, chronic inflammation, endothelial dysfunction, disturbances in fluid and electrolyte balance, and the frequent presence of comorbid conditions contribute to the elevated perioperative risk observed in this population. This review discusses the epidemiology, pathophysiological mechanisms, and clinical significance of chronic kidney disease as a risk factor for adverse postoperative outcomes in abdominal surgery. Additionally, current approaches to perioperative assessment and management of patients with CKD are presented to reduce complications and improve surgical outcomes.
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Filev et al. (2026) conducted a review in Chronic kidney disease in abdominal surgery. Chronic kidney disease was evaluated on Postoperative complications (acute kidney injury, infectious complications, cardiovascular events, and hospital mortality). Chronic kidney disease is associated with a significantly higher risk of postoperative complications, including acute kidney injury, infections, cardiovascular events, and mortality in abdominal surgery.
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