Key result
Coronary embolism from LAA thrombus triggers MINOCA in a patient with rheumatic valvular AF.
Why the study?
MINOCA represents a diagnostic challenge with multiple underlying mechanisms, including coronary embolism.
Case Report (n=1)
No
This case highlights the importance of considering coronary embolism from a left atrial appendage thrombus in patients presenting with MINOCA, particularly those with rheumatic valvular atrial fibrillation.
Answers are grounded in this paper and cite their sources.
May support targeted embolism evaluation in MINOCA; leaves open need for prospective validation.
Myocardial infarction with non-obstructive coronary arteries (MINOCA) represents a diagnostic challenge with multiple underlying mechanisms, including coronary embolism. We report the case of a 50-year-old woman with a history of rheumatic fever who was admitted for acute chest pain. Electrocardiography showed atrial fibrillation with inferolateral ischemic changes, and elevated troponin levels confirmed myocardial infarction. Transthoracic echocardiography revealed moderate mitral stenosis, severe aortic stenosis, and left atrial enlargement. Coronary angiography demonstrated thrombotic occlusion of the second obtuse marginal branch without significant atherosclerotic disease. Transesophageal echocardiography identified a left atrial appendage thrombus, supporting a cardioembolic mechanism. This case emphasizes the importance of considering coronary embolism in MINOCA, particularly in patients with valvular atrial fibrillation, and highlights the role of a structured diagnostic approach in guiding diagnosis and management.
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Moujahid et al. (2026) conducted a case report in Myocardial Infarction With Non-obstructive Coronary Arteries (MINOCA) (n=1). Coronary embolism from left atrial appendage thrombus was evaluated. Coronary embolism from a left atrial appendage thrombus was identified as the cause of MINOCA in a 50-year-old woman with rheumatic valvular atrial fibrillation.
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