Key result
Higher CCI is linked to ~24% more postoperative complications after hip fracture surgery in patients >80.
Why the study?
Hip fracture mortality and morbidity pose a significant healthcare burden, making preoperative identification of high-risk patients essential.
Does preoperative Charlson comorbidity index predict postoperative complications and in-hospital mortality in patients older than 80 years undergoing hip fracture surgery?
Observational (n=498)
No
Does preoperative Charlson comorbidity index predict postoperative complications and in-hospital mortality in patients older than 80 years undergoing hip fracture surgery?
Odds Ratio: 1.243 (95% CI 1.02–1.516)
p-value: p=0.031
The Charlson comorbidity index is an independent predictor of postoperative complications and in-hospital mortality in patients over 80 years old undergoing hip fracture surgery.
May aid preoperative risk counseling in octogenarians with hip fractures; leaves open whether CCI-targeted interventions improve outcomes.
INDUCTION: The mortality and morbidity in hip fracture is a big healthcare burden. How to identify risk patients preoperatively is important. The aim of study was to evaluate the risk factors of postoperative complications and mortality in patients older than 80 years old after hip fracture surgery. METHODS: Patients older than 80 years old with the diagnosis of hip fracture who had surgical treatment from February 2013 to June 2021 at a single center in China were included for analysis. The primary outcome were postoperative complications and in-hospital mortality. Binary logistic regression was used to confirm the relationship between preoperative factors and postoperative complications/mortality. RESULTS: 498 patients were included for analysis. 176 patients developed 265 episodes of complications and the incidence of postoperative complication was 35.3%. Postoperative pulmonary infection was the most common complication, followed by cardiovascular complications and postoperative delirium. And there were 10 postoperative in-hospital deaths (2.0%). Preoperative Charlson comorbidity index(CCI) was associated with postoperative complications (OR = 1.243, 95%CI 1.020-1.516, P = 0.031) and mortality (OR = 2.303, 95%CI 1.351-3.925, P = 0.002). However, American society of Anesthesiologists (ASA) score was not an independent risk factor for postoperative complication and mortality. CONCLUSION: CCI was the risk factor of poor postoperative outcome for patients older than 80 years old after hip fracture surgery. And CCI can be used as the potential tool of risk stratification for this group of patients. TRIAL REGISTRATION: This study had been registered in www.chictr.org.cn and the registration ID was ChiCTR2400085291 on June 4th 2024.
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Zhang et al. (2025) conducted an observational in Hip fracture (n=498). Preoperative Charlson comorbidity index (CCI) was evaluated on Postoperative complications (OR 1.243, 95% CI 1.020-1.516, p=0.031). Higher preoperative Charlson comorbidity index was significantly associated with increased odds of postoperative complications (OR 1.243) and in-hospital mortality (OR 2.303) in patients older than 80 years after hip fracture surgery.
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