Intramedullary Spinal Glioblastoma in a Patient With Lynch Syndrome: A Case Challenging CNS Immune Boundaries (P2-6.011)

Ricardo Vivanco Menoscal; Rina Yadav; Andre Ene; Flavius Raslau; Catherine Garcia; John Villano

doi:10.1212/wnl.0000000000216533

June 9, 2026Neurology

Intramedullary Spinal Glioblastoma in a Patient With Lynch Syndrome: A Case Challenging CNS Immune Boundaries (P2-6.011)

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Key Points

This report details a unique case of spinal glioblastoma in a young individual with Lynch syndrome, which complicates immune response understanding.
Case report of a young man with glioblastoma and Lynch syndrome
Assessment of spinal cord involvement
Review of immune response in glioblastoma context
Patient exhibited spinal cord glioblastoma alongside pre-existing intracranial glioblastoma
Case emphasizes challenges to central nervous system immune boundaries
Findings contribute to understanding tumor behavior in Lynch syndrome context

Implication

Case report examines spinal glioblastoma in a young man with Lynch syndrome, highlighting immune challenges.

Abstract

To present an interesting case of spinal cord involvement of Glioblastoma (GBM) in a young man with Lynch syndrome (LS) and previously stable intracranial GBM.

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Cite This Study

Menoscal et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf300faef96ed7f055908 https://doi.org/10.1212/wnl.0000000000216533

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Intramedullary Spinal Glioblastoma in a Patient With Lynch Syndrome: A Case Challenging CNS Immune Boundaries (P2-6.011)

Key Points

Implication

Abstract

Discussion

Cite This Study

Intramedullary Spinal Glioblastoma in a Patient With Lynch Syndrome: A Case Challenging CNS Immune Boundaries (P2-6.011)

Key Points

Implication

Abstract

Discussion

Cite This Study

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