Intravenous Thrombolysis Before Thrombectomy vs Thrombectomy Alone: A Meta-analysis on Technical and Safety Outcomes (P8-4.021)

Francis Demiraj; G Srinivasan; Praveen Nandha Kumar Pitchan Velammal; Klesta Cocoli; Noorul Hidhaya; Tejaswin Mariappan; Haran Srinivasan; R. Ashwini

doi:10.1212/wnl.0000000000215988

June 9, 2026Neurology

Intravenous Thrombolysis Before Thrombectomy vs Thrombectomy Alone: A Meta-analysis on Technical and Safety Outcomes (P8-4.021)

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Key Points

The research aims to compare the technical efficacy and safety of intravenous thrombolysis prior to mechanical thrombectomy against direct thrombectomy in acute ischemic stroke.
Conducted a meta-analysis of existing studies on thrombolysis and thrombectomy.
Analyzed technical outcomes and safety metrics from both intervention approaches.
Thrombolysis before thrombectomy showed improved technical efficacy in acute ischemic stroke.
Safety outcomes were comparable between both methods, with no significant increase in complications.

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Implication

Meta-analysis compares technical efficacy and safety of thrombolysis before thrombectomy in acute ischemic stroke, indicating potential benefits.

Abstract

To compare technical efficacy and safety of intravenous thrombolysis prior to mechanical thrombectomy versus direct thrombectomy in acute ischemic stroke

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Cite This Study

Demiraj et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf300faef96ed7f055909 https://doi.org/10.1212/wnl.0000000000215988

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Intravenous Thrombolysis Before Thrombectomy vs Thrombectomy Alone: A Meta-analysis on Technical and Safety Outcomes (P8-4.021)

Key Points

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Implication

Abstract

Discussion

Cite This Study

Intravenous Thrombolysis Before Thrombectomy vs Thrombectomy Alone: A Meta-analysis on Technical and Safety Outcomes (P8-4.021)

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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