Differential Response to Transcranial Direct Current Stimulation Across Primary Progressive Aphasia Subtypes: A Case Study Analysis (P6-13.008)

Oluwasijibomi Osunkoya; Catherine Norise; Roy Hamilton

doi:10.1212/wnl.0000000000215406

June 9, 2026Neurology

Differential Response to Transcranial Direct Current Stimulation Across Primary Progressive Aphasia Subtypes: A Case Study Analysis (P6-13.008)

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Key Points

This analysis investigates how HD-tDCS, combined with mCILT, affects different aphasia subtypes.
Participants received HD-tDCS paired with mCILT.
Comparison was made between naPPA and lvPPA subtypes.
Distinct benefits were observed for each aphasia subtype after intervention.
naPPA participants showed a notable improvement in language skills.

Implication

Case study examines tDCS effects on language improvement in nonfluent and logopenic aphasia variants, suggesting distinct responses.

Abstract

To examine whether frontal high-definition tDCS (HD-tDCS) paired with modified constraint-induced language therapy (mCILT) differentially benefits participants with the nonfluent/agrammatic variant (naPPA) versus logopenic variant (lvPPA).

Discussion

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Cite This Study

Osunkoya et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf300faef96ed7f055920 https://doi.org/10.1212/wnl.0000000000215406

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Differential Response to Transcranial Direct Current Stimulation Across Primary Progressive Aphasia Subtypes: A Case Study Analysis (P6-13.008)

Key Points

Implication

Abstract

Discussion

Cite This Study

Differential Response to Transcranial Direct Current Stimulation Across Primary Progressive Aphasia Subtypes: A Case Study Analysis (P6-13.008)

Key Points

Implication

Abstract

Discussion

Cite This Study

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