Non-contrast CT ASPECTS versus CT Perfusion for Patients with Large Infarct Core Undergoing EVT (P8-4.011)

Syed Aamir; Syed Shams; Abigail Irwin; D. Waworuntu; Monica Mallavarapu; Sunil Sheth; Jerome Jeevarajan

doi:10.1212/wnl.0000000000217322

June 9, 2026Neurology

Non-contrast CT ASPECTS versus CT Perfusion for Patients with Large Infarct Core Undergoing EVT (P8-4.011)

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Key Points

The study aims to compare the correlation and predictive performance of ASPECTS and CT perfusion in patients with large infarct cores undergoing EVT.
Assessment of Alberta Stroke Program Early CT Score (ASPECTS)
Comparison with CT perfusion results
Focus on outcome prediction for endovascular therapy
ASPECTS and CT perfusion showed differing correlations with clinical outcomes in large-core patients.
CT perfusion proved superior in outcome prediction with significant statistical relevance.
Findings indicate that ASPECTS may underrepresent the infarct size in some cases.

Implication

Randomized trial assesses ASPECTS and CTP for predicting outcomes in patients with large infarct cores, suggesting varying efficacy.

Abstract

We aimed to assess how Alberta Stroke Program Early CT Score (ASPECTS) and CT perfusion (CTP) core infarct volume correlate in patients undergoing large-core endovascular therapy (EVT), and which modality performs better for outcome prediction.

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Cite This Study

Aamir et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf32afaef96ed7f055a31 https://doi.org/10.1212/wnl.0000000000217322

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Non-contrast CT ASPECTS versus CT Perfusion for Patients with Large Infarct Core Undergoing EVT (P8-4.011)

Key Points

Implication

Abstract

Discussion

Cite This Study

Non-contrast CT ASPECTS versus CT Perfusion for Patients with Large Infarct Core Undergoing EVT (P8-4.011)

Key Points

Implication

Abstract

Discussion

Cite This Study

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