Multiple, Simultaneous, Severe Neurological Complications of ATRA and ATO During Acute Promyelocytic Leukemia Treatment: A Case Report (P3-6.003)

Arth Pahwa; Jenna Miller; Barrie Zerwic; Aaron Carlson; Brian Sauer

doi:10.1212/wnl.0000000000215171

June 9, 2026Neurology

Multiple, Simultaneous, Severe Neurological Complications of ATRA and ATO During Acute Promyelocytic Leukemia Treatment: A Case Report (P3-6.003)

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Key Points

This case report aims to highlight the occurrence of severe neurological complications associated with ATRA and ATO therapy in APL patients.
Descriptive case report of a patient undergoing ATRA and ATO therapy for acute promyelocytic leukemia.
Monitoring and documenting the neurological complications that arose during treatment.
Multiple severe neurological complications presented during treatment, including but not limited to specific symptoms related to ATRA and ATO administration.

Implication

Case report reveals severe neurological complications during ATRA and ATO therapy for acute promyelocytic leukemia, suggesting caution in treatment.

Abstract

To report a case of multiple neurologic complications of all-trans retinoic acid (ATRA) and arsenic trioxide (ATO) therapy for acute promyelocytic leukemia (APL).

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Cite This Study

Pahwa et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf32afaef96ed7f055aad https://doi.org/10.1212/wnl.0000000000215171

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Multiple, Simultaneous, Severe Neurological Complications of ATRA and ATO During Acute Promyelocytic Leukemia Treatment: A Case Report (P3-6.003)

Key Points

Implication

Abstract

Discussion

Cite This Study

Multiple, Simultaneous, Severe Neurological Complications of ATRA and ATO During Acute Promyelocytic Leukemia Treatment: A Case Report (P3-6.003)

Key Points

Implication

Abstract

Discussion

Cite This Study

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