Identifies antiviral properties of Toxicodendron vernicifluum extracts against coronavirus, suggesting new treatment possibilities.
ethanol extract (TVE) shows antiviral effects against human coronavirus. TVE treatment inhibited coronavirus replication as well as viral infectivity. To elucidate the active constituents responsible for this activity, comprehensive phytochemical profiling of TVE was performed using UPLC-Q-Orbitrap-MS, leading to the tentative identification of major phytochemicals. Based on this analytical profiling, individual compounds were isolated from TVE and evaluated for antiviral activity against coronavirus. We found that ethyl gallate, fisetin, butin, sulfuretin, and gallic acid exhibit antiviral activity against coronavirus.
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Choi et al. (2026) studied this question.
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