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June 9, 2026Neurology

Case Report: Diagnostic Challenges and Atypical MRI Findings in Two Cases of Creutzfeldt-Jakob Disease (P3-7.001)

Joshua Lopez Ayesha Syed Elena Quiñonez del Cid Anahit Mehrabyan Michael Wang

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Key Points

This report highlights the diagnostic challenges faced in identifying atypical MRI presentations of sporadic Creutzfeldt-Jakob Disease (CJD).
Presented two case analyses with unique MRI findings of sporadic CJD.
Investigated diagnostic procedures and challenges for accurate identification.
Reviewed clinical symptoms and diagnostic imaging results.
Demonstrated atypical MRI characteristics that confused initial diagnoses.
Highlighted the need for updated awareness of CJD's diverse presentations.

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Implication

Case report reveals ongoing diagnostic challenges in identifying atypical MRI findings of CJD.

Abstract

We present two cases of sporadic CJD highlighting various ongoing diagnostic challenges.

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Cite This Study

Lopez et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf32afaef96ed7f055b33 https://doi.org/10.1212/wnl.0000000000212953

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