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June 13, 2026

Subsequent Malignant Neoplasms in Childhood Cancer Survivors: Identifying Risks and Screening Recommendations.

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Authors

KBKerri BecktellKCKelly CotchettRVRebecca Volmy

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Overview

Randomized trial identifies risks and screening recommendations for subsequent malignant neoplasms in childhood cancer survivors, suggesting tailored approaches for patient care.

Key Points

  • The aim is to identify risk factors and develop screening recommendations for subsequent malignant neoplasms in childhood cancer survivors.
  • Reviewed existing literature on SMNs and associated risks.
  • Analyzed risk factors such as radiation, chemotherapy, and genetic predispositions.
  • Evaluated current screening guidelines for individualized patient needs.
  • Estimated SMN risk in survivors ranges from 2% to 20%.
  • Identified multiple factors contributing to SMN development, necessitating tailored screening.
  • Current guidelines vary, highlighting the need for personalized approaches.

Cite This Study

Becktell et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf32afaef96ed7f055b89https://doi.org/10.1016/j.hoc.2026.02.002
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Second Malignant Neoplasms Following Treatment for Childhood Cancer: A Population‐Based Registry Study2026
  2. 2Increased risk of subsequent neoplasm after hematopoietic stem cell transplantation in 5-year survivors of childhood acute lymphoblastic leukemia2024 · 9 citations
  3. 3Surviving childhood cancer: the hidden threat of second malignancies2026 · 1 citations
  4. 4Second malignant neoplasms within 5 years from first primary diagnosis in pediatric oncology patients in Canada: a population-based retrospective cohort study2024 · 5 citations
  5. 5Secondary Neoplasm in Survivors of Childhood Hematological Malignancies—Systematic Review2026