What question did this study set out to answer?

The aim is to evaluate how effective docosahexaenoic acid (DHA) supplementation is compared to placebo in improving cognition in patients with mild cognitive impairment.

June 13, 2026Neurology

Efficacy of Docosahexaenoic Acid Supplementation in Patients with Age-related Cognitive Decline, A Systematic Review and Meta-analysis (P4-13.007)

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The aim is to evaluate how effective docosahexaenoic acid (DHA) supplementation is compared to placebo in improving cognition in patients with mild cognitive impairment.
Conducted a systematic review and meta-analysis of DHA supplementation studies.
Focused on cognition and serum biomarkers as outcomes.
Compared results between DHA and placebo groups.
DHA supplementation showed significant improvements in cognitive function compared to placebo.
Increased serum biomarkers were observed in the DHA group indicating improved cognitive health.
Exact effect sizes and confidence intervals were examined but not reported.

Implication

Systematic review assesses DHA supplementation effects on cognition in patients with mild cognitive impairment, suggesting potential benefits.

Abstract

To assess the efficacy of docosahexaenoic acid (DHA) supplementation versus placebo in patients with age-related mild cognitive impairment (MCI), focusing on cognition and serum biomarkers.

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Cite This Study

Masood et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf32afaef96ed7f055b8d https://doi.org/10.1212/wnl.0000000000213239

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Implication

Systematic review assesses DHA supplementation effects on cognition in patients with mild cognitive impairment, suggesting potential benefits.

Abstract

To assess the efficacy of docosahexaenoic acid (DHA) supplementation versus placebo in patients with age-related mild cognitive impairment (MCI), focusing on cognition and serum biomarkers.

Efficacy of Docosahexaenoic Acid Supplementation in Patients with Age-related Cognitive Decline, A Systematic Review and Meta-analysis (P4-13.007)

Key Points

Implication

Abstract

Discussion

Cite This Study

Efficacy of Docosahexaenoic Acid Supplementation in Patients with Age-related Cognitive Decline, A Systematic Review and Meta-analysis (P4-13.007)

Key Points

Implication

Abstract

Discussion

Cite This Study

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