Rapidly Progressive Anti-MAG Neuropathy Case Report: Breaking the Slow Progression Paradigm (P1-9.008)

June 9, 2026Neurology

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Key Points

This report aims to describe a rare case of IgM lambda anti-MAG neuropathy presenting with rapid progression contrary to typical CIDP profiles.
Case report detailing clinical presentation and progression of the patient
Assessment of IgM lambda anti-MAG levels
Comparison to classic chronic inflammatory demyelinating polyneuropathy (CIDP) characteristics
The patient showed an unusually rapid decline in motor and sensory functions over a short period.
Elevated levels of IgM lambda anti-MAG were confirmed.
Findings challenge the traditional understanding of neuropathy progression in CIDP.

Case report reveals rapid progression in IgM lambda anti MAG neuropathy, indicating a need for reevaluation of existing paradigms.

To report an unusual case IgM lambda anti MAG neuropathy, with CIDP like presentation and rapid progression.

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Sa’alek et al. (2026) studied this question.

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