CHANTER Banter: Investigating Histopathology in a Case of Cerebellar, Hippocampal, and Basal Nuclei, Transient Edema, and Restricted Diffusion (CHANTER) Syndrome (P5-5.013)

Elliott Delgado; Sharanya Ramakrishnan; Naman Bareja; Elizabeth Rosen; Joshua Kornbluth

doi:10.1212/wnl.0000000000217783

June 9, 2026Neurology

CHANTER Banter: Investigating Histopathology in a Case of Cerebellar, Hippocampal, and Basal Nuclei, Transient Edema, and Restricted Diffusion (CHANTER) Syndrome (P5-5.013)

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Key Points

The aim is to characterize the pathophysiologic mechanisms of CHANTER syndrome following opioid use through histopathologic data.
Case report detailing the individual affected by CHANTER syndrome after opioid use.
Histopathological examination conducted to analyze tissue changes.
Focused on brain regions including cerebellum, hippocampus, and basal nuclei.
Histopathologic findings indicate transient edema in cerebellar and hippocampal regions.
Evidence of restricted diffusion in affected brain areas.
Identified specific changes associated with opioid-induced pathophysiology.

Implication

Case report investigates histopathological characterization of CHANTER syndrome following opioid exposure, suggesting underlying mechanisms.

Abstract

To report a case of Cerebellar, Hippocampal, and Basal Nuclei, Transient Edema and Restricted Diffusion (CHANTER) after opioid use, and provide histopathologic data to aid in characterization of pathophysiologic mechanisms.

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Cite This Study

Delgado et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf36efaef96ed7f055de7 https://doi.org/10.1212/wnl.0000000000217783

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CHANTER Banter: Investigating Histopathology in a Case of Cerebellar, Hippocampal, and Basal Nuclei, Transient Edema, and Restricted Diffusion (CHANTER) Syndrome (P5-5.013)

Key Points

Implication

Abstract

Discussion

Cite This Study

CHANTER Banter: Investigating Histopathology in a Case of Cerebellar, Hippocampal, and Basal Nuclei, Transient Edema, and Restricted Diffusion (CHANTER) Syndrome (P5-5.013)

Key Points

Implication

Abstract

Discussion

Cite This Study

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