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June 9, 2026Neurology

A Single-center Experience with Omaveloxolone in Friedreich Ataxia (P4-16.013)

Martina Gramaglia Alessio Sarnataro Giorgia Puorro Angela Marsili Angelo Rendina Chiara Pane Francesco Saccà

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Key Points

To assess the clinical effectiveness and outcomes of Omaveloxolone in patients with Friedreich Ataxia.
Single-center observational evaluation
Patient-reported outcomes assessment
Analysis of treatment effectiveness over time.
Patients showed improvement in clinical outcomes using Omaveloxolone over the evaluation period.
Treatment was generally well-tolerated with minimal side effects reported.

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Implication

Evaluates clinical outcomes of omaveloxolone in Friedreich Ataxia, indicating treatment effectiveness.

Abstract

Evaluate the real-world use of Omaveloxolone in Friedreich Ataxia (FA).

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Cite This Study

Gramaglia et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf36efaef96ed7f055dfe https://doi.org/10.1212/wnl.0000000000216348

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Early Experience on Omaveloxolone in Adult Patients with Friedreich’s Ataxia: A Real-world Observational Study (P4-16.006)Observational Study · 2026
2Evolution of Friedreich’s Ataxia Management Across Established and Emerging Therapies—Systematic Review and Meta-AnalysisMeta-Analysis · 2026
3Synthesis and Biological Profile of Omaveloxolone: The Cornerstone for Friedreich Ataxia Treatment2025 · 6 citations
4Managing Aminotransferase Elevations in Patients with Friedreich Ataxia Treated with Omaveloxolone: A Review and Expert Opinion on Use ConsiderationsReview · 2025 · 10 citations
5The MOXIe Trial of Omaveloxolone in Friedreich Ataxia: Exploring the Transient Nature of Treatment-emergent Adverse Events (P7-3.016)2024 · 2 citations