What question did this study set out to answer?

The aim is to report an unusual case of progressive multifocal leukoencephalopathy with brainstem involvement leading to locked-in syndrome.

June 13, 2026Neurology

Progressive Multifocal Leukoencephalopathy with Atypical Radiological Presentation and Locked-in Syndrome: A Case Report (P9-3.008)

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Case report describes atypical brain imaging and outcomes in a patient with locked-in syndrome, indicating diagnostic importance.

The aim is to report an unusual case of progressive multifocal leukoencephalopathy with brainstem involvement leading to locked-in syndrome.
Descriptive case report focusing on clinical presentation and brain imaging findings.
Analysis of the relationship between clinical symptoms and radiological findings.
Documented atypical imaging patterns associated with brainstem lesions.
Highlighted the evolution of symptoms leading to locked-in syndrome.

Calvache et al. (2026) studied this question.

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