Imaging Proxies of Glymphatic Flow as a Mechanism for Executive Dysfunction in Cancer-related Cognitive Impairment (P7-12.009)

Sophie Kushman; Alique Topalian; Brady Williamson; Tess Brewer; Rhonna Shatz; Melinda Butsch Kovacic

doi:10.1212/wnl.0000000000215062

June 9, 2026Neurology

Imaging Proxies of Glymphatic Flow as a Mechanism for Executive Dysfunction in Cancer-related Cognitive Impairment (P7-12.009)

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Key Points

The study aims to explore the links between sleep quality, glymphatic flow proxies, and executive function in cancer survivors, focusing on modifiable factors.
Evaluated associations among cancer survivors using imaging proxies of glymphatic flow.
Assessed sleep quality and executive function through standardized measures.
Identified potential mechanisms connecting these variables.
Poor sleep quality is associated with decreased glymphatic flow and impaired executive function.
Identified modifiable factors that may enhance cognitive health in cancer survivors.

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Implication

Study reveals associations between glymphatic flow and cognitive function in cancer survivors, indicating potential modifiable factors.

Abstract

This study aims to characterize associations between sleep quality, proxies of glymphatic flow, and executive function among cancer survivors, identifying modifiable factors and mechanisms of action for CRCI.

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Cite This Study

Kushman et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf393faef96ed7f05608c https://doi.org/10.1212/wnl.0000000000215062

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Imaging Proxies of Glymphatic Flow as a Mechanism for Executive Dysfunction in Cancer-related Cognitive Impairment (P7-12.009)

Key Points

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Implication

Abstract

Discussion

Cite This Study

Imaging Proxies of Glymphatic Flow as a Mechanism for Executive Dysfunction in Cancer-related Cognitive Impairment (P7-12.009)

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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