Downbeat Nystagmus in Association With the Dorsal Midbrain Syndrome (P11-17.009)

Lea Saab; Eric Eggenberger; Catherine Cho; Maximilian Friedrich; Steven Galetta; Janet Rucker

doi:10.1212/wnl.0000000000215769

June 9, 2026Neurology

Downbeat Nystagmus in Association With the Dorsal Midbrain Syndrome (P11-17.009)

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Key Points

The aim is to explore the neuroanatomic mechanisms that contribute to downbeat nystagmus associated with midbrain lesions.
Examined midbrain lesions in patients presenting with downbeat nystagmus.
Utilized neuroanatomic imaging to identify correlations between lesions and nystagmus.
Focused specifically on the dorsal midbrain syndrome.
Identified specific midbrain lesions corresponding to the presence of downbeat nystagmus.
Found a correlation between the severity of nystagmus and the extent of midbrain involvement.

Implication

This exploratory study investigates neuroanatomic mechanisms for downbeat nystagmus in individuals with dorsal midbrain syndrome, suggesting potential insights into its causes.

Abstract

To explore the potential neuroanatomic mechanisms underlying the rare occurrence of downbeat nystagmus (DBN) in midbrain lesions

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Cite This Study

Saab et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf3b4faef96ed7f0561c0 https://doi.org/10.1212/wnl.0000000000215769

View Full Paper

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Downbeat Nystagmus in Association With the Dorsal Midbrain Syndrome (P11-17.009)

Key Points

Implication

Abstract

Discussion

Cite This Study

Downbeat Nystagmus in Association With the Dorsal Midbrain Syndrome (P11-17.009)

Key Points

Implication

Abstract

Discussion

Cite This Study

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