A Multicenter, Real-world Natural History Study on Timed 25-foot Walk Outcome Measures in Stiff Person Syndrome (P4-2.003)

Scott Newsome; Lowe Mallory; Hanyeh Afshar; Kelli Money; Asli Buyukkurt; Herbert Chen; Barrett Crawford; Sadie Eggmann; Aisha Elfasi; Angeliki Fillippatou; Munther Queisi; Daniela Riveros Acosta; Andrea Salazar-Camelo; Jadyn Zook; Norma Guzmán‐Becerra; Jennifer Leslie; Skye Geherin; Amanda Piquet

doi:10.1212/wnl.0000000000213225

Key Points

This research aims to evaluate how the timed 25-foot walk (T25FW) changes over time in patients with stiff person syndrome (SPS).
Conducted as a multicenter study across various locations
Focused on measuring timed 25-foot walk outcomes
Involved real-world clinical observations of patients with SPS
Documented longitudinal changes in timed 25-foot walk performance
Observed variations in walking speed and mobility outcomes over time in SPS patients
Identified patterns that may indicate disease progression and response to treatment

Implication

Multicenter study evaluates longitudinal changes in timed 25-foot walk measures in stiff person syndrome, suggesting insights into disease progression.

Abstract

To evaluate longitudinal changes in timed-25-foot walk (T25FW) among patients with stiff person syndrome (SPS).

Discussion

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Cite This Study

Newsome et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf3b4faef96ed7f056244 https://doi.org/10.1212/wnl.0000000000213225

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A Multicenter, Real-world Natural History Study on Timed 25-foot Walk Outcome Measures in Stiff Person Syndrome (P4-2.003)

Key Points

Implication

Abstract

Discussion

Cite This Study

A Multicenter, Real-world Natural History Study on Timed 25-foot Walk Outcome Measures in Stiff Person Syndrome (P4-2.003)

Key Points

Implication

Abstract

Discussion

Cite This Study

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