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June 13, 2026International Journal of Innovative Technologies in Social ScienceOpen Access

Autoimmune Hepatitis: Diagnostic Challenges and Risk Factors – A Narrative Review

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Authors

MGMarta GóralKBKatarzyna BednarczukASAleksandra Irena Skuza

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Overview

Narrative review highlights the complexities of diagnosing autoimmune hepatitis and identifies contributing risk factors.

Key Points

  • This review examines the diagnostic challenges and risk factors associated with autoimmune hepatitis (AIH).
  • Narrative review of existing literature on AIH diagnosis and pathogenesis.
  • Analysis of serological, biochemical, and histopathological diagnostic criteria.
  • Exploration of genetic and environmental factors influencing disease susceptibility.
  • AIH presents with diverse clinical profiles, complicating consistent diagnosis.
  • Key diagnostic markers include autoantibodies and elevated immunoglobulin G, though specificity issues persist.
  • Integration of histopathological findings and an understanding of immune dysregulation is vital for accurate diagnosis.

Cite This Study

Góral et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf3b4faef96ed7f056388https://doi.org/10.31435/ijitss.2(50).2026.5373
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The intestinal and biliary microbiome in autoimmune liver disease—current evidence and concepts2022 · 55 citations
  2. 2Partners in Leaky Gut Syndrome: Intestinal Dysbiosis and Autoimmunity2021 · 361 citations
  3. 3Acute presentation of autoimmune hepatitis: a multicentre study with detailed histological evaluation in a large cohort of patients2017 · 82 citations