Significant Sensorimotor Polyneuropathy Caused by Dry Beriberi Secondary to Semaglutide-associated Thiamine Deficiency (P3-9.004)

Chloe Cohan; Liam Townley; Erik Ortega

doi:10.1212/wnl.0000000000215813

June 9, 2026Neurology

Significant Sensorimotor Polyneuropathy Caused by Dry Beriberi Secondary to Semaglutide-associated Thiamine Deficiency (P3-9.004)

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Key Points

The aim is to report a case of severe sensorimotor polyneuropathy resulting from thiamine deficiency linked to semaglutide use.
Case description of sensorimotor polyneuropathy triggered by thiamine deficiency.
Emphasized the role of semaglutide in contributing to malnutrition and subsequent deficiency.
Severe symptoms of sensorimotor polyneuropathy were observed due to thiamine deficiency.
Early intervention is crucial for managing the effects of thiamine deficiency caused by semaglutide.

Implication

Case report describes severe sensorimotor polyneuropathy from thiamine deficiency due to semaglutide, highlighting early intervention importance.

Abstract

To describe a case of severe sensorimotor polyneuropathy secondary to thiamine deficiency induced by semaglutide-associated malnutrition, emphasizing the importance of early recognition and intervention.

Discussion

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Cite This Study

Cohan et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf3d6faef96ed7f0563a5 https://doi.org/10.1212/wnl.0000000000215813

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Significant Sensorimotor Polyneuropathy Caused by Dry Beriberi Secondary to Semaglutide-associated Thiamine Deficiency (P3-9.004)

Key Points

Implication

Abstract

Discussion

Cite This Study

Significant Sensorimotor Polyneuropathy Caused by Dry Beriberi Secondary to Semaglutide-associated Thiamine Deficiency (P3-9.004)

Key Points

Implication

Abstract

Discussion

Cite This Study

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