Thalamic Structural Connectivity Alterations in Essential Tremor Associated with REM Sleep Behaviour Disorder (P5-17.008)

Elisa Bortolin; Salvatore Mazzeo; Camilla Calomino; Rita Nisticò; Giulia Bruschi; Maria Vittoria Corbari; Andrea Quattrone; Aldo Quattrone; Fabiana Novellino; Massimo Filippi; Maria Salsone

doi:10.1212/wnl.0000000000216402

June 9, 2026Neurology

Thalamic Structural Connectivity Alterations in Essential Tremor Associated with REM Sleep Behaviour Disorder (P5-17.008)

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Key Points

The main aim is to explore the thalamic structural connectivity differences in essential tremor patients with and without REM sleep behavior disorder.
Graph theoretical analysis was used to evaluate thalamic regions.
Participants included essential tremor patients categorized by the presence of REM sleep behavior disorder.
Significant alterations in structural connectivity in thalamic areas were observed in essential tremor patients with REM sleep behavior disorder as compared to those without.
The study reveals unique connectivity patterns that may be associated with the clinical presentation of essential tremor.

Implication

Investigates thalamic connectivity in essential tremor patients, highlighting impacts of sleep disorders.

Abstract

We aimed at investigating investigated thalamic regions in Essential Tremor (ET) patients with and without REM sleep behavior disorder (RBD), using a graph theoretical analysis.

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Cite This Study

Bortolin et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf3d6faef96ed7f0563e3 https://doi.org/10.1212/wnl.0000000000216402

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Thalamic Structural Connectivity Alterations in Essential Tremor Associated with REM Sleep Behaviour Disorder (P5-17.008)

Key Points

Implication

Abstract

Discussion

Cite This Study

Thalamic Structural Connectivity Alterations in Essential Tremor Associated with REM Sleep Behaviour Disorder (P5-17.008)

Key Points

Implication

Abstract

Discussion

Cite This Study

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