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June 9, 2026Neurology

Metastatic Malignant Peripheral Nerve Sheath Tumor in a Patient With Neurofibromatosis Type One: A Diagnostic and Management Challenge (P8-6.008)

Haidara Kherbek Sumayya Naz Bashar Saour Elysia James

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Key Points

To explore the diagnostic difficulties and management strategies for metastatic malignant peripheral nerve sheath tumors in patients with neurofibromatosis type one.
Case analysis of a patient with neurofibromatosis type one and malignant peripheral nerve sheath tumor.
Assessment of diagnostic procedures and treatment approaches used.
Identified complexities in diagnosing metastatic tumors due to overlapping clinical features with neurofibromatosis.
Emphasized the need for tailored management strategies for effective treatment.

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Implication

Case report highlights diagnostic and management challenges of metastatic tumors in affected individuals.

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Cite This Study

Kherbek et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf3d6faef96ed7f056502 https://doi.org/10.1212/wnl.0000000000215140

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Diagnostic challenges of the neurofibroma-malignant peripheral nerve sheath tumor spectrum in neurofibromatosis type 1: illustrative case.2025
2Diagnosis and management of malignant peripheral nerve sheath tumors: Current practice and future perspectivesClinical Trial · 2019 · 96 citations
3A Pediatric Case of Neurofibromatosis Type 1–Associated Malignant Peripheral Nerve Sheath Tumor of the Scalp2025
4High-Grade Malignant Peripheral Nerve Sheath Tumor Arising From Common Peroneal Nerve Neurofibroma2024 · 1 citations
5Large Malignant Peripheral Nerve Sheath Tumor Arising From the Sciatic Nerve in a Patient With Neurofibromatosis Type 1Original Research · 2026

More related papers

Giant malignant peripheral nerve sheath tumor: Illustrative case and surgical technique2026
Plexiform Neurofibromas and Malignant Peripheral Nerve Sheath Tumors in Adults with Neurofibromatosis Type 1: Clinical Insights from a Large Cohort2026
Peripheral nerve sheath tumors associated with neurofibromatosis type 12025

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