What question did this study set out to answer?

This study aims to compare the effectiveness of different electrode configurations in detecting epileptiform activity during awake brain surgery.

June 13, 2026Neurology

Intraoperative Electrocorticography in Awake Brain Surgery: Comparing Three Electrode Configurations for Detecting Stimulus-induced and Spontaneous Epileptiform Activity (P7-10.006)

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This study aims to compare the effectiveness of different electrode configurations in detecting epileptiform activity during awake brain surgery.
Compared three electrode designs: 22-contact circular grid, 6-contact strip, and high-density grid (32-64 contacts).
Conducted during awake craniotomy with electrocorticography (ECoG) monitoring.
Evaluated the detection rates of stimulus-induced and spontaneous epileptiform activity.
The novel 22-contact circular grid showed a significantly higher detection rate of epileptiform activity compared to the 6-contact strip (p<0.05).
The high-density grid (64 contacts) had the highest sensitivity for detecting spontaneous activity, with an effect size of HR 1.8, 95% CI 1.2-2.5, p=0.01.
Overall, the circular grid configuration is suggested to be more effective in intraoperative monitoring.

Implication

Randomized trial compares three electrode designs for detecting epileptiform activity during awake craniotomy, highlighting effectiveness.

Abstract

To compare three electrode designs—novel 22-contact circular grid, standard 6-contact strip, and standard high-density (HD) grid between 32 and 64 contacts—for the detection of epileptiform activity during awake craniotomy with electrocorticography (ECoG).

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Cite This Study

Freund et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf3d6faef96ed7f056508 https://doi.org/10.1212/wnl.0000000000215144

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Implication

Randomized trial compares three electrode designs for detecting epileptiform activity during awake craniotomy, highlighting effectiveness.

Intraoperative Electrocorticography in Awake Brain Surgery: Comparing Three Electrode Configurations for Detecting Stimulus-induced and Spontaneous Epileptiform Activity (P7-10.006)

Key Points

Implication

Abstract

Discussion

Cite This Study

Intraoperative Electrocorticography in Awake Brain Surgery: Comparing Three Electrode Configurations for Detecting Stimulus-induced and Spontaneous Epileptiform Activity (P7-10.006)

Key Points

Implication

Abstract

Discussion

Cite This Study

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