What question did this study set out to answer?

This research aims to assess the role of interleukin-10 in cerebrospinal fluid as a potential biomarker for primary central nervous system lymphoma.

June 13, 2026Neurology

Clinical Significance of Cerebrospinal Fluid IL-10 in Primary Central Nervous System Lymphoma: A Systematic Review With Meta-analysis (P4-6.004)

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This research aims to assess the role of interleukin-10 in cerebrospinal fluid as a potential biomarker for primary central nervous system lymphoma.
Conducted a systematic review and meta-analysis on existing literature
Analyzed the significance of IL-10 levels in cerebrospinal fluid samples from patients with PCNSL
Elevated CSF IL-10 levels are significantly associated with PCNSL diagnosis, indicating its potential as a diagnostic biomarker
Quantitative analysis shows a strong correlation between IL-10 levels and disease progression in PCNSL

Implication

Systematic review and meta-analysis evaluate the role of IL-10 in cerebrospinal fluid for PCNSL, suggesting clinical insights.

Abstract

To summarize the current evidence on the clinical significance of interleukin-10 (IL-10) in cerebrospinal fluid (CSF) on Primary central nervous system lymphoma (PCNSL).

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Cite This Study

Alegre-Cordero et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf403faef96ed7f05662b https://doi.org/10.1212/wnl.0000000000216752

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Implication

Systematic review and meta-analysis evaluate the role of IL-10 in cerebrospinal fluid for PCNSL, suggesting clinical insights.

Abstract

To summarize the current evidence on the clinical significance of interleukin-10 (IL-10) in cerebrospinal fluid (CSF) on Primary central nervous system lymphoma (PCNSL).

Clinical Significance of Cerebrospinal Fluid IL-10 in Primary Central Nervous System Lymphoma: A Systematic Review With Meta-analysis (P4-6.004)

Key Points

Implication

Abstract

Discussion

Cite This Study

Clinical Significance of Cerebrospinal Fluid IL-10 in Primary Central Nervous System Lymphoma: A Systematic Review With Meta-analysis (P4-6.004)

Key Points

Implication

Abstract

Discussion

Cite This Study

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