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June 9, 2026Neurology

Pentad of Horizontal Gaze Paresis, Diplopia, Jaw Dystonia, Gait Abnormalities, and Ataxia: Case Report of a Distinct Anti-Ri Syndrome (P10-1.001)

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Key Points

This report aims to identify and describe a distinct syndrome within the Anti-Ri spectrum.
Case report detailing clinical symptoms of a patient with the syndrome.
Observation of symptoms including horizontal gaze paresis and ataxia.
The patient exhibited a unique combination of horizontal gaze paresis, diplopia, and jaw dystonia.
Gait abnormalities and ataxia were also noted as part of the syndrome.

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Implication

Case report reveals a unique syndrome in the Anti-Ri spectrum, suggesting new diagnostic insights.

Abstract

To report a distinct syndrome within Anti-Ri spectrum.

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Cite This Study

Ali Karimi (2026) studied this question.

synapsesocial.com/papers/6a2cf403faef96ed7f056631 https://doi.org/10.1212/wnl.0000000000215622

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Gait instability, ophthalmoplegia, and chorea with orofacial dyskinesia in a man with anti-Ri antibodies: a case report2024 · 4 citations
2Lost in Cognition: Paraneoplastic Rhombencephalitis With Anti-Ri/Antineuronal Nuclear Antibody Type 2 (ANNA-2) Antibodies Presenting as Rapid-Onset Cognitive Decline and Ophthalmoplegia-Ataxia With Reversible Brainstem Lesion2025
3Paraneoplastic Rhombencephalitis with Anti-Ri/ANNA-2 Antibodies Presenting as Rapid Onset Cognitive Decline and Ophthalmoplegia-ataxia with Reversible Brainstem Lesion: A Case Report (P1-14.015)2024
4Clinical features of paraneoplastic neurologic syndromes with anti-Ri antibodies: PRISMA systematic reviewSystematic Review · 2026
5Anti-GQ1b antibody syndrome presenting as acute ophthalmoplegia with pupillary involvement and blepharoptosis: a case report and literature reviewClinical Trial · 2026

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