Genome sequences of four virulent Klebsiella pneumoniae phages targeting multidrug-resistant clinical isolates from Ethiopia

Assefa Asnakew Abebe; Molalegne Bitew; Alemayehu Godana Birhanu; Dawit Hailu Alemayehu; Abaysew Ayele; Keyru Tuki; Yimer Demssie; Lanchisl Tsegaye Mulualem; Tesfaye Sisay Tessema

doi:10.1128/mra.01213-25

June 11, 2026Microbiology Resource AnnouncementsOpen Access

Genome sequences of four virulent Klebsiella pneumoniae phages targeting multidrug-resistant clinical isolates from Ethiopia

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Key Points

To characterize the genome sequences of four lytic bacteriophages that target multidrug-resistant Klebsiella pneumoniae isolates.
Isolated four different lytic bacteriophages from clinical samples.
Conducted genome sequencing to determine the size and structure of the phage genomes.
Analyzed lytic activity against multidrug-resistant Klebsiella pneumoniae isolates.
The size of the bacteriophage genomes ranged from 15,773 to 166,437 base pairs.
All four phages showed effective lytic activity against multidrug-resistant clinical isolates.
The identified bacteriophage genera include Taipeivirus, Drulisvirus, Przondovirus, and Webervirus.

Implication

Examines lytic activity of four bacteriophages against multidrug-resistant Klebsiella pneumoniae, indicating therapeutic potential.

Abstract

We present genome sequences of four lytic bacteriophages targeting multidrug-resistant (MDR) Klebsiella pneumoniae isolates. The bacteriophages belong to the genera Taipeivirus , Drulisvirus , Przondovirus , and Webervirus . These phages exhibit promising lytic activity against MDR K. pneumoniae clinical isolates. The genomes of the bacteriophages ranged in size from 15,773 to 166,437 bp.

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Cite This Study

Abebe et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf4aefaef96ed7f056f46 https://doi.org/10.1128/mra.01213-25

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Genome sequences of four virulent Klebsiella pneumoniae phages targeting multidrug-resistant clinical isolates from Ethiopia

Key Points

Implication

Abstract

Discussion

Cite This Study

Genome sequences of four virulent Klebsiella pneumoniae phages targeting multidrug-resistant clinical isolates from Ethiopia

Key Points

Implication

Abstract

Discussion

Cite This Study

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