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The study aims to investigate the factors contributing to high insecticide resistance among Anopheles gambiae populations in Ghana.

June 13, 2026BMC Infectious DiseasesOpen Access

High resistance of Anopheles gambiae s.L. populations to public health insecticides in Ghana: contribution of domestic and agricultural pesticide use

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Randomized trial examines insecticide resistance in Anopheles gambiae, indicating links to pesticide use.

The study aims to investigate the factors contributing to high insecticide resistance among Anopheles gambiae populations in Ghana.
Anopheles larvae were collected from eight sites and reared to adults.
WHO insecticide susceptibility assays were performed on female Anopheles gambiae s.l. to assess resistance.
Surveys evaluated household insecticide use and agricultural pesticide application.
Coastal zone populations showed 50-85.9% mortality for pyrethroids at 10x exposure.
Sahel zone populations had >98% mortality for pyrethroids at 10x exposure.
High prevalence of L1014F mutation was noted at all sites, suggesting a genetic basis for resistance.

Yanney et al. (2026) studied this question.

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