A Review on the Pharmacognostic and Antidiabetic Potential of Aerva Lanata and Anacyclus Pyrethrum in Polyherbal Therapy

Diabetes mellitus is a chronic metabolic disorder characterized by persistent hyperglycemia resulting from impaired insulin secretion, insulin action, or both. The present review focuses on the pharmacognostic, phytochemical, and pharmacological properties of Aerva lanata and Anacyclus pyrethrum and their potential role in polyherbal therapy for diabetes mellitus. Aerva lanata, belonging to the family Amaranthaceae, is traditionally used for the management of diabetes, urinary disorders, inflammation, and kidney diseases, whereas Anacyclus pyrethrum, a member of the family Asteraceae, is widely recognized for its antidiabetic, neuroprotective, antioxidant, and rejuvenating properties. Both plants contain important phytoconstituents such as flavonoids, alkaloids, tannins, terpenoids, phenolic compounds, and glycosides that contribute significantly to their therapeutic activities. This review summarizes the taxonomical classification, botanical description, geographical distribution, traditional uses, phytochemical constituents, and pharmacological activities of these medicinal plants. Particular emphasis has been given to their antidiabetic mechanisms, antioxidant potential, and the concept of synergistic action in polyherbal formulations. Overall, Aerva lanata and Anacyclus pyrethrum demonstrate promising therapeutic potential in diabetes management and may serve as valuable candidates for the development of effective and safe polyherbal antidiabetic formulations. Further pharmacological and clinical investigations are necessary to validate their efficacy, safety, and therapeutic applications in modern healthcare systems.