What question did this study set out to answer?

This study aims to evaluate the safety of hypoxic red blood cell transfusions in patients with hematological malignancies and burns.

June 13, 2026Journal of Blood MedicineOpen Access

A Clinical Investigation of Hypoxic Red Blood Cell Administration in Patients with Transfusion-Dependent Hematological Malignancies and Burns

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Authors

HRHåkon ReikvamHaukeland University Hospital TLTurid Helen Felli LundeHaukeland University Hospital EKEinar KristoffersenHaukeland University Hospital

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Implication

Randomized trial investigates safety of hypoxic red blood cell transfusion in hematological malignancies and burns, indicating it could be a viable option.

Key Points

This study aims to evaluate the safety of hypoxic red blood cell transfusions in patients with hematological malignancies and burns.
Single-center pilot safety study
Twenty patients included: 10 with hematological malignancies, 10 with burns
Primary outcome: adverse events within 24 hours post-transfusion; secondary outcome: changes in hemoglobin levels
No adverse events related to hypoxic red blood cell transfusion were reported.
Mean change in hemoglobin for hematological malignancies group: 1.2 ± 0.5 g/dL.
Mean change in hemoglobin for burn group: 0.3 ± 1.0 g/dL.

Cite This Study

Reikvam et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf5aefaef96ed7f05796b https://doi.org/10.2147/jbm.s573232

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Implication

Randomized trial investigates safety of hypoxic red blood cell transfusion in hematological malignancies and burns, indicating it could be a viable option.

A Clinical Investigation of Hypoxic Red Blood Cell Administration in Patients with Transfusion-Dependent Hematological Malignancies and Burns

Discussion

Member takes

Implication

Key Points

Cite This Study

A Clinical Investigation of Hypoxic Red Blood Cell Administration in Patients with Transfusion-Dependent Hematological Malignancies and Burns

Discussion

Member takes

Implication

Key Points

Cite This Study

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