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June 13, 2026Phytomedicine PlusOpen Access

Effect of Pentadiplandra brazzeana Baill Root-Supplemented Diet on Selected Lactogenic Biomarkers in Postpartum Wistar Rats

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Authors

MEMercy Nwakamaswor EgbuleBabcock UniversityAOAkinsola OyelakinSeattle Children's HospitalGAGodswill AnyasorBabcock University

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Implication

Randomized trial investigates pentadiplandra brazzeana root effects on lactogenic markers in postpartum rats, suggesting hormonal benefits.

Key Points

  • This study aims to examine the impact of pentadiplandra brazzeana root supplementation on lactogenic biomarkers in postpartum Wistar rats.
  • Thirty postpartum Wistar rats were divided into six groups and fed different diets.
  • Serum levels of hormonal markers and immunoglobulins were assessed using ELISA, with Azgp1 gene expression evaluated via PCR.
  • Data were analyzed using descriptive and inferential statistics at a 5% significance level.
  • PBRSD significantly increased estrogen, prolactin, oxytocin, FSH, and immunoglobulin G levels compared to control (p < 0.05).
  • Weight and immunoglobulin A levels decreased in the PBRSD groups compared to controls.
  • Azgp1 gene expression increased from 0.07 ± 0.04 in controls to 1.15 ± 0.05 in treated rats (p < 0.05).

Cite This Study

Egbule et al. (2026) studied this question.

synapsesocial.com/papers/6a2cf6d7faef96ed7f058876https://doi.org/10.1016/j.phyplu.2026.101011
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