Randomized trial examined the coinfection dynamics of Acinetobacter baumannii in COVID-19 patients, suggesting the need for ongoing pathogen monitoring.
Key Points
This research aims to investigate the epidemiology and genetic characteristics of Acinetobacter baumannii during COVID-19 coinfections.
Collected 179 A. baumannii clinical isolates from a COVID-19 center in Mexico.
Performed genetic screening for carbapenemases, PFGE analysis, and antimicrobial resistance profiling.
Analyzed phylogenomics and genome content diversity among the isolates.
76.24% of isolates carried the bla OXA-23 gene indicating high antimicrobial resistance.
The outbreak involved multiple sequence types (ST2057/ST473), with ST1837/ST369 appearing endemic.
Infections were associated with invasive procedures rather than genomic adaptations of the bacteria.