Key result
High country-level rates of in-hospital revascularization following STEMI were associated with lower 30-day mortality compared to lower and intermediate rates (5.1% vs 6.9% and 6.5%; P<0.001).
Why the study?
Does a higher country-level rate of in-hospital revascularization reduce mortality in patients with STEMI receiving fibrinolytic therapy?
Population
16,949 patients with acute ST-elevation myocardial infarction enrolled in the ASSENT-2 fibrinolytic trial…
Comparison
Highest tertile of in-hospital revascularization… vs Lower tertiles of in-hospital revascularization…
Design
Cohort
Follow-up
1 year
Authors
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Should not yet change post-STEMI revascularization practices; leaves open whether country-level rates causally affect mortality.
Observational (n=16,949)
Yes
Does a higher country-level rate of in-hospital revascularization reduce mortality in patients with STEMI receiving fibrinolytic therapy?
Absolute Event Rate: 5.1% vs 6.9%
p-value: p=<0.001
Higher country-level rates of in-hospital revascularization following fibrinolysis for STEMI are associated with reduced 30-day and 1-year mortality.
Milan Gupta (2003) conducted an observational in Acute ST-elevation myocardial infarction (n=16,949). Highest tertile of in-hospital revascularization rates (>39%) vs. Lower tertiles of in-hospital revascularization rates (<15%, 15-39%) was evaluated on 30-day mortality (p=<0.001). High country-level rates of in-hospital revascularization following STEMI were associated with lower 30-day mortality compared to lower and intermediate rates (5.1% vs 6.9% and 6.5%; P<0.001).
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