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June 14, 2026British Journal of Biomedical ScienceOpen Access

Artificial intelligence approaches in biological age prediction: current status and challenges

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Authors

GWGuangjun WangPDPengcheng DingZLZihui Li

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Overview

Review demonstrates AI methods improve biological age prediction, highlighting current challenges and future directions.

Key Points

  • This review evaluates the use of artificial intelligence in predicting biological age and addresses the challenges faced in this field.
  • Systematic overview of AI approaches for biological age prediction.
  • Analysis of biomarker selection, feature engineering, and model development techniques.
  • Discussion of challenges such as data heterogeneity and model interpretability.
  • AI-driven models show promise for improving biological age prediction across diverse populations.
  • Highlighted challenges include insufficient model interpretability and barriers to clinical application.
  • Future research should integrate multi-omics data to enhance predictive accuracy and interpretability.

Cite This Study

Wang et al. (2026) studied this question.

synapsesocial.com/papers/6a2e4429b1cc60ccdea8a0c7https://doi.org/10.3389/bjbs.2026.16141
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Integrating chronological aging and asynchronous aging for enhanced biological age prediction using artificial intelligence model2026
  2. 2A scoping review on aging and cardiovascular diseases - Molecular mediators and artificial intelligence-based advanced diagnostic methods2026
  3. 3Machine Learning Approaches for Biological Age Estimation: Narrative Review of Non-Invasive and Cost-Effective Methodologies2025
  4. 4Functional, molecular, and digital measurements of biological age2026
  5. 5Artificial Intelligence-Driven Biological Age Prediction Model Using Comprehensive Health Checkup Data: Development and Validation Study2025 · 6 citations