International Session 55　　Olfaction

Background : COVID-19 is linked to severe opportunistic infections, notably rhino-orbital-cerebral mucormycosis (ROCM) , which has high morbidity and mortality.Objectives : To evaluate the clinical profile, management, outcomes, and prognostic factors of ROCM in post-COVID-19 patients.Methods : We retrospectively analyzed 68 ROCM patients treated at Saidu Group of Teaching Hospital, Swat, Pakistan, from January-August 2025.Demographics, comorbidities, clinical presentation, disease extent, surgical approaches, and outcomes were reviewed.Results : Most patients were male(61％) , aged 35-73 years ; 91． 17％ had diabetes, 88． 3％ prior COVID-19.Common features included facial pain, orbital involvement, and vision loss.Multisite disease involving paranasal sinuses, orbit, and brain was frequent.All underwent surgical debridement, mainly via modified endoscopic Denker's approach(88． 23％) .Mortality was 32． 3％ ; 62％ achieved disease-free status.Intracranial extension(p＜0． 001)and uncontrolled diabetes(p＝0． 016)predicted mortality.Conclusion : COVID-19-associated ROCM primarily affects diabetic patients ; early diagnosis, prompt surgery, and strict glycemic control improve survival.