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June 14, 2026JDS CommunicationsOpen Access

Measuring cytokines in quarter milk samples with a fluorescent bead-based multiplex assay.

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Authors

ASAnja SipkaMWMatthias Wieland

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Overview

Randomized trial demonstrates cytokine measurement in milk samples, suggesting improved mastitis diagnostics.

Key Points

  • This research aimed to validate a multiplex assay for measuring cytokines in quarter milk samples affected by mastitis.
  • Analyzed cytokine concentrations in milk samples from 17 dairy farms in central New York.
  • Utilized a fluorescent bead-based multiplex assay to quantify IL-10, TNF-α, and IFN-γ.
  • Categorized samples based on bacteriological culture results, including major mastitis pathogens.
  • COLIFORM samples showed significantly higher IL-10 and TNF-α concentrations than all other groups.
  • STREP samples exhibited increased IFN-γ and TNF-α compared to S. AUREUS, NO GROWTH, and HEALTHY samples.
  • No significant differences were found between S. AUREUS, NO GROWTH, and HEALTHY samples.

Cite This Study

Sipka et al. (2026) studied this question.

synapsesocial.com/papers/6a2e4524b1cc60ccdea8a632https://doi.org/10.3168/jdsc.2026-1038
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